Breast conservation versus mastectomy
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Breast Cancer Research and Treatment. This study was performed to assess patterns and outcomes of BCT for T3 tumors. Patients with skin or chest wall involvement were excluded. Patients having clinical T3 tumors were analyzed to determine outcomes based upon presentation, with those having pathologic T3 tumors, subsequently assessed, irrespective of presentation. Overall survival OS was analyzed using multivariable Cox proportional hazards models, with adjusted survival curves estimated using inverse probability weighting.
Breast conserving surgery versus mastectomy: cancer practice by general surgeons in Iran
Simple mastectomy and modified radical mastectomy - Mayo Clinic
Using two multicenter retrospective studies on breast cancer, a pooled analysis was performed among patients with pTN1 TNBC. All patients received taxane-based adjuvant chemotherapy. The median age of all patients was 48 years range, 24 to 70 years. Other characteristics were not significantly different between the two groups. In pTN1 TNBC, breast conservation therapy achieved better locoregional recurrencefree, disease-free, and overall survival rates compared with mastectomy. Triple-negative breast cancer TNBC has the higher risk for locoregional recurrence than any other molecular subtypes in the absence of effective targeted agents which are known to further decrease locoregional recurrence [ 1 ].
Mastectomy versus lumpectomy plus radiation therapy
Under certain circumstances, people with breast cancer have the opportunity to choose between total removal of a breast mastectomy and breast-conserving surgery lumpectomy followed by radiation. Lumpectomy followed by radiation is likely to be equally as effective as mastectomy for people with only one site of cancer in the breast and a tumor under 4 centimeters. Clear margins are also a requirement no cancer cells in the tissue surrounding the tumor.
Breast-conserving surgery BCS is a good option for many women with early-stage cancers. The main advantage is that a woman keeps most of her breast. However, she will in most cases also need radiation therapy, given by a radiation oncologist a doctor who specializes in radiation. This type of surgery is typically done in an outpatient surgery center, and an overnight stay in the hospital is usually not needed.
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